Glycosyl bis-porphyrin conjugates: synthesis and potential application in PDT.

@article{Sol2006GlycosylBC,
  title={Glycosyl bis-porphyrin conjugates: synthesis and potential application in PDT.},
  author={Vincent Sol and Vincent Chaleix and Yves Champavier and Robert Granet and Y. Huang and Pierre Krausz},
  journal={Bioorganic & medicinal chemistry},
  year={2006},
  volume={14 23},
  pages={7745-60}
}
Syntheses of new glycosylated neutral and cationic porphyrin dimers linked at the meso-position via a flexible hydrocarbon chain are described. A detailed 1H and 13C NMR study allows their complete structural elucidation. The UV-visible, fluorescence and MALDI mass spectra are also presented. Photocytotoxicities of these compounds against K562 leukaemia cell line are compared to those of Photofrin II.