Glycosphingolipid synthesis is essential for MDCK cell differentiation.


Glycosphingolipids (GSLs), which are highly concentrated at the apical membrane of polarized epithelial cells, are key components of cell membranes and are involved in a large number of processes. Here, we investigated the ability of hypertonicity (high salt medium) to induce Madin-Darby Canine Kidney (MDCK) cell differentiation and found an increase in GSL… (More)
DOI: 10.1016/j.bbalip.2012.02.009