Glycosaminoglycans in crystal-surface binding substances and their role in calcium oxalate crystal growth.

@article{Yoshimura1997GlycosaminoglycansIC,
  title={Glycosaminoglycans in crystal-surface binding substances and their role in calcium oxalate crystal growth.},
  author={Koichi Yoshimura and Toshiaki Yoshioka and Osamu Miyake and Mikio Honda and Satoshi Yamaguchi and Takuo Koide and Akihiko Okuyama},
  journal={British journal of urology},
  year={1997},
  volume={80 1},
  pages={
          64-8
        }
}
OBJECTIVE To clarify the role of glycosaminoglycans (GAGs) in crystal-surface binding substances (CSBS) on the growth of calcium oxalate crystals in urine. MATERIALS AND METHODS Urine samples (24 h) were collected from healthy men (aged 25-42 years) and CSBS were obtained from the pooled urine samples. The CSBS were digested with heparitinase or proteinase and the inhibition of crystal growth assessed before and after enzyme digestion. Anion-exchange chromatography and high-performance liquid… CONTINUE READING
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