Glycosaminoglycan Analysis by Cryogenic Messenger-Tagging IR Spectroscopy Combined with IMS-MS.

Abstract

We combine ion mobility spectrometry with cryogenic, messenger-tagging, infrared spectroscopy and mass spectrometry to identify different isomeric disaccharides of chondroitin sulfate (CS) and heparan sulfate (HS), which are representatives of two major subclasses of glycosaminoglycans. Our analysis shows that while CS and HS disaccharide isomers have… (More)
DOI: 10.1021/acs.analchem.7b01467

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Cite this paper

@article{Khanal2017GlycosaminoglycanAB, title={Glycosaminoglycan Analysis by Cryogenic Messenger-Tagging IR Spectroscopy Combined with IMS-MS.}, author={Neelam Khanal and Chiara Masellis and Michael Z. Kamrath and David E. Clemmer and Thomas R Rizzo}, journal={Analytical chemistry}, year={2017}, volume={89 14}, pages={7601-7606} }