Glycosaminoglycan (GAG) binding surfaces for characterizing GAG-protein interactions.

@article{Robinson2012GlycosaminoglycanB,
  title={Glycosaminoglycan (GAG) binding surfaces for characterizing GAG-protein interactions.},
  author={David J. Robinson and David J. Buttle and Robert D. Short and S L Sally L McArthur and David A. Steele and J. N. D. Whittle},
  journal={Biomaterials},
  year={2012},
  volume={33 4},
  pages={1007-16}
}
Glycosaminoglycans play an important role in tissue organisation through interactions with a diverse range of proteins, growth factors and other chemokines. In this report, we demonstrate the GAG-binding 'fingerprint' of two important GAG-binding proteins - osteoprotogerin and TIMP-3. The technique uses a straightforward method for attaching GAGs to assay… CONTINUE READING