Glycopyrrolate methobromide: 2. comparison with atropine sulphate in anaesthesia.

  title={Glycopyrrolate methobromide: 2. comparison with atropine sulphate in anaesthesia.},
  author={K A Oduro},
  journal={Canadian Anaesthetists' Society journal},
  volume={22 4},
  • K A Oduro
  • Published 1975 in Canadian Anaesthetists' Society journal
A double blind study of 98 patients was undertaken to compare the clinical usefulness of atropine and glycopyrrolate for pre-anaesthetic medication and their relative effectiveness in antagonizing the muscarinic effects of neostigmine methylsulphate given to reverse neuromuscular blockade. Intramuscular administration of atropine 0.4 mg or of glycopyrrolate 0.2 mg produced the same degree of dryness of the pharynx. However, glycopyrrolate was found to be a more potent antagonizer of the… CONTINUE READING