Glycoproteomic characterization of carriers of the CD15/Lewisx epitope on Hodgkin's Reed-Sternberg cells

@inproceedings{Powlesland2010GlycoproteomicCO,
  title={Glycoproteomic characterization of carriers of the CD15/Lewisx epitope on Hodgkin's Reed-Sternberg cells},
  author={Alex S. Powlesland and Mar{\'i}a Marcela Barrio and Jos{\'e} Mordoh and Paul Hitchen and Anne Dell and Kurt Drickamer and M Evangeline Taylor},
  booktitle={BMC Biochemistry},
  year={2010}
}
The Lewisx trisaccharide, also referred to as the CD15 antigen, is a diagnostic marker used to distinguish Hodgkin's lymphoma from other lymphocytic cancers. However, the role of such fucosylated structures remains poorly understood, in part because carriers of Lewisx structures on Hodgkin's Reed-Sternberg cells have not been identified. GalMBP, an engineered carbohydrate-recognition protein that binds selectively to oligosaccharides with paired terminal galactose and fucose residues, has been… CONTINUE READING
6 Extracted Citations
25 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 25 references

Similar Papers

Loading similar papers…