Glycoproteins E and I of Marek's disease virus serotype 1 are essential for virus growth in cultured cells.

@article{Schumacher2001GlycoproteinsEA,
  title={Glycoproteins E and I of Marek's disease virus serotype 1 are essential for virus growth in cultured cells.},
  author={Daniel Schumacher and Bernd Karsten Tischer and S. Madhusudhan Reddy and Nikolaus Osterrieder},
  journal={Journal of virology},
  year={2001},
  volume={75 23},
  pages={11307-18}
}
The role of glycoprotein E (gE) and gI of Marek's disease virus serotype 1 (MDV-1) for growth in cultured cells was investigated. MDV-1 mutants lacking either gE (20DeltagE), gI (20DeltagI), or both gE and gI (20DeltagEI) were constructed by recE/T-mediated mutagenesis of a recently established infectious bacterial artificial chromosome (BAC) clone of MDV-1 (D. Schumacher, B. K. Tischer, W. Fuchs, and N. Osterrieder, J. Virol. 74:11088-11098, 2000). Deletion of either gE or gI, which form a… CONTINUE READING

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