Glycoprotein IIb/IIIa inhibitors: The resurgence of tirofiban.

  title={Glycoprotein IIb/IIIa inhibitors: The resurgence of tirofiban.},
  author={Shawn King and Marintha R. Short and Cassidy Harmon},
  journal={Vascular pharmacology},
Glycoprotein (GP) IIb/IIIa inhibitors block platelet aggregation, reducing thrombotic events in acute coronary syndrome. They are most often utilized in patients who likely have an intracoronary thrombus. Tirofiban, eptifibatide, and abciximab are the three GP IIb/IIIa inhibitors approved for use in the United States. Each agent has unique pharmacological properties. They all have a rapid onset and are most often utilized in conjunction with heparin. Tirofiban, in particular, fell out of favor… CONTINUE READING

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