Glycopeptide insensitive Staphylococcus aureus subdural empyema treated with linezolid and rifampicin.

Abstract

A 4-year-old boy had surgical debulking of a cerebral astrocytoma followed by chemotherapy. He developed a subdural empyema with a teicoplanin and methicillin resistant Staphylococcus aureus. He was successfully treated with surgical drainage and 6 weeks of antibiotic therapy which included linezolid, rifampicin and metronidazole. Linezolid may be successful in treating other CNS infections caused by antibiotic resistant gram-positive organisms.

DOI: 10.1016/j.jinf.2008.06.023

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@article{Gallagher2008GlycopeptideIS, title={Glycopeptide insensitive Staphylococcus aureus subdural empyema treated with linezolid and rifampicin.}, author={Ruairi M. Gallagher and Billy Pizer and James A. Ellison and F. Andrew I. Riordan}, journal={The Journal of infection}, year={2008}, volume={57 5}, pages={410-3} }