Glycomics: an integrated systems approach to structure-function relationships of glycans

@article{Raman2005GlycomicsAI,
  title={Glycomics: an integrated systems approach to structure-function relationships of glycans},
  author={R. Raman and S. Raguram and G. Venkataraman and J. Paulson and R. Sasisekharan},
  journal={Nature Methods},
  year={2005},
  volume={2},
  pages={817-824}
}
  • R. Raman, S. Raguram, +2 authors R. Sasisekharan
  • Published 2005
  • Biology, Medicine
  • Nature Methods
  • In comparison with genomics and proteomics, the advancement of glycomics has faced unique challenges in the pursuit of developing analytical and biochemical tools and biological readouts to investigate glycan structure-function relationships. Glycans are more diverse in terms of chemical structure and information density than are DNA and proteins. This diversity arises from glycans' complex nontemplate-based biosynthesis, which involves several enzymes and isoforms of these enzymes… CONTINUE READING

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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 82 REFERENCES
    A genetic approach to Mammalian glycan function.
    • 534
    • PDF
    Essentials of Glycobiology
    • 2,303
    • PDF
    Role of glycosylation in development.
    • 588