Glycomics: an integrated systems approach to structure-function relationships of glycans

@article{Raman2005GlycomicsAI,
  title={Glycomics: an integrated systems approach to structure-function relationships of glycans},
  author={Rahul Raman and S. Raguram and Ganesh Venkataraman and James C. Paulson and Ram Sasisekharan},
  journal={Nature Methods},
  year={2005},
  volume={2},
  pages={817-824}
}
In comparison with genomics and proteomics, the advancement of glycomics has faced unique challenges in the pursuit of developing analytical and biochemical tools and biological readouts to investigate glycan structure-function relationships. Glycans are more diverse in terms of chemical structure and information density than are DNA and proteins. This diversity arises from glycans' complex nontemplate-based biosynthesis, which involves several enzymes and isoforms of these enzymes… 
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