Glycolytic inhibition as a strategy for developing calorie restriction mimetics

@article{Ingram2011GlycolyticIA,
  title={Glycolytic inhibition as a strategy for developing calorie restriction mimetics},
  author={Donald K Ingram and George S. Roth},
  journal={Experimental Gerontology},
  year={2011},
  volume={46},
  pages={148-154}
}
  • D. Ingram, G. Roth
  • Published 2011
  • Medicine, Biology, Engineering
  • Experimental Gerontology
Calorie restriction (CR) remains the most robust environmental intervention for altering aging processes and increasing healthspan and lifespan. Emerging from progress made in many nonhuman models, current research has expanded to formal, controlled human studies of CR. Since long-term CR requires a major commitment of will power and long-term negative consequences remain to be determined, the concept of a calorie restriction mimetic (CRM) has become a new area of investigation within… Expand
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