Glycolytic flux occurs in Drosophila melanogaster recovering from camptothecin treatment.

Abstract

Camptothecin (CPT) and CPT-derived drugs are widely used against gynaecological and colorectal cancers. On account of their mechanism of action these drugs target rapidly dividing cells and may have an adverse effect on normal tissues. We sought to investigate their impact on normal cells by using Drosophila as a model. We investigated the possible… (More)
DOI: 10.1097/CAD.0b013e32833e2f60

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