Glycolysis can prevent non-synaptic excitatory amino acid release during hypoxia.

@article{Longuemare1994GlycolysisCP,
  title={Glycolysis can prevent non-synaptic excitatory amino acid release during hypoxia.},
  author={M C Longuemare and Michael P Hill and Raymond A Swanson},
  journal={Neuroreport},
  year={1994},
  volume={5 14},
  pages={1789-92}
}
Release of excitatory amino acids (EAAs) contributes to neuronal death during cerebral ischemia. EAA release occurs by both synaptic and non-synaptic mechanisms. However, studies in vivo yield conflicting estimates of their relative importance. This disparity may reflect differing degrees of substrate deprivation produced by various in vivo models. We used primary rat astrocyte cultures to establish the relationship between substrate deprivation, energy failure, and non-synaptic EAA release… CONTINUE READING

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