Glycohistochemical characterization of vascular muscle cell destruction in CADASIL subjects by lectins, neoglycoconjugates and galectin‐specific antibodies

@article{BrulinFardoux2003GlycohistochemicalCO,
  title={Glycohistochemical characterization of vascular muscle cell destruction in CADASIL subjects by lectins, neoglycoconjugates and galectin‐specific antibodies},
  author={P. Brulin-Fardoux and C. Godfrain and C. Maurage and J. De Reuck and J. Hauw and H. Kaltner and N. Bovin and H. Gabius and M-M Ruchoux and R. Kiss and I. Camby},
  journal={Neuropathology and Applied Neurobiology},
  year={2003},
  volume={29}
}
  • P. Brulin-Fardoux, C. Godfrain, +8 authors I. Camby
  • Published 2003
  • Biology, Medicine
  • Neuropathology and Applied Neurobiology
  • CADASIL (Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) is a type of small‐artery stroke and vascular dementia‐inducing pathology of the brain. In order to explain the molecular mechanisms behind the alterations to the blood vessels in CADASIL subjects, we scrutinized the expression of glycan and glycan‐binding sites in the wall of vessels taken from five such subjects (vs. five control subjects matched for age and sex). Specimens were taken from the… CONTINUE READING
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