Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy.

@article{Luo2009GlycogenSK,
  title={Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy.},
  author={Jia Luo},
  journal={Cancer letters},
  year={2009},
  volume={273 2},
  pages={194-200}
}
Glycogen synthase kinase 3beta (GSK3beta), a multifunctional serine/threonine kinase found in all eukaryotes, had been initially identified as a key regulator of insulin-dependent glycogen synthesis. It is now known that GSK3beta functions in diverse cellular processes including proliferation, differentiation, motility and survival. Aberrant regulation of GSK3beta has been implicated in a range of human pathologies including non-insulin-dependent diabetes mellitus, cardiovascular disease, some… CONTINUE READING
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