Glycogen synthase kinase-3β gene is associated with antidepressant treatment response in Chinese major depressive disorder

@article{Tsai2008GlycogenSK,
  title={Glycogen synthase kinase-3β gene is associated with antidepressant treatment response in Chinese major depressive disorder},
  author={S-J Tsai and Y J Liou and C Hong and Younger W-Y Yu and T Chen},
  journal={The Pharmacogenomics Journal},
  year={2008},
  volume={8},
  pages={384-390}
}
Evidence suggests that glycogen synthase kinase-3β (GSK3B) activity is increased significantly in the brain of patients with major depressive disorders (MDD). Inhibition of GSK3B is thought to be a key feature in the therapeutic mechanism of antidepressants. To investigate whether common genetic variants in the GSK3B gene are associated with MDD and the therapeutic response to antidepressants, four polymorphisms (rs334558 (−50 T>C), rs13321783 (IVS7+9227 A>G), rs2319398 (IVS7+11660 G>T) and… CONTINUE READING
31 Extracted Citations
22 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 31 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 22 references

Similar Papers

Loading similar papers…