Glycogen synthase kinase 3: A key regulator of cellular fate

Abstract

The serine/threonine kinase glycogen synthase kinase-3 (GSK-3) was initially identified as a key regulator of insulin-dependent glycogen synthesis. GSK-3 was subsequently shown to function in a wide range of cellular processes including differentiation, growth, motility and apoptosis. Aberrant regulation of GSK-3 has been implicated in a range of human… (More)
DOI: 10.1007/s00018-007-7045-7

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@article{Forde2007GlycogenSK, title={Glycogen synthase kinase 3: A key regulator of cellular fate}, author={J. E. Forde and Travis Dale}, journal={Cellular and Molecular Life Sciences}, year={2007}, volume={64}, pages={1930-1944} }