GlycoFi's technology to control the glycosylation of recombinant therapeutic proteins.

@article{Beck2010GlycoFisTT,
  title={GlycoFi's technology to control the glycosylation of recombinant therapeutic proteins.},
  author={Alain Beck and Olivier Cochet and Thierry Wurch},
  journal={Expert opinion on drug discovery},
  year={2010},
  volume={5 1},
  pages={
          95-111
        }
}
IMPORTANCE OF THE FIELD Therapeutic properties of many glycoproteins strongly depend on the composition of their glycans. Most of the current approved glycoproteins are produced in mammalian cell lines, which yield mixture of different glycoforms close to the human one but not fully identical. Glyco-engineering is being developed as a method to control the composition of carbohydrates. Many alternative glycoprotein productions systems are actively investigated including new-engineered yeast… CONTINUE READING
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