Glycinergic synaptic transmission in the cochlear nucleus of mice with normal hearing and age-related hearing loss.

@article{Xie2013GlycinergicST,
  title={Glycinergic synaptic transmission in the cochlear nucleus of mice with normal hearing and age-related hearing loss.},
  author={Ruili Xie and Paul B. Manis},
  journal={Journal of neurophysiology},
  year={2013},
  volume={110 8},
  pages={
          1848-59
        }
}
The principal inhibitory neurotransmitter in the mammalian cochlear nucleus (CN) is glycine. During age-related hearing loss (AHL), glycinergic inhibition becomes weaker in CN. However, it is unclear what aspects of glycinergic transmission are responsible for weaker inhibition with AHL. We examined glycinergic transmission onto bushy cells of the anteroventral CN in normal-hearing CBA/CaJ mice and in DBA/2J mice, a strain that exhibits an early onset AHL. Glycinergic synaptic transmission was… CONTINUE READING
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