Glycinergic synaptic currents in the deep cerebellar nuclei.

  title={Glycinergic synaptic currents in the deep cerebellar nuclei.},
  author={Christine M. Pedroarena and Susanne B. Kamphausen},
  volume={54 5},
Despite evidence of local glycinergic circuits in the mature cerebellar nuclei the result of their activation remains unknown. Here, using whole cell recordings in rat cerebellar slices we demonstrated that after postnatal day 17 (>P17) glycinergic IPSCs can be readily evoked in large deep cerebellar nuclear neurons (DCNs), in the same way as in neonatal DCNs (P7-P10). Spontaneous glycinergic IPSCs were very rare but direct presynaptic depolarization by superfusion with elevated potassium… CONTINUE READING