Glycine site N-methyl-D-aspartate receptor antagonist 7-CTKA produces rapid antidepressant-like effects in male rats.

@article{Zhu2013GlycineSN,
  title={Glycine site N-methyl-D-aspartate receptor antagonist 7-CTKA produces rapid antidepressant-like effects in male rats.},
  author={Wei-li Zhu and Shen-jun Wang and Meng-meng Liu and Hai-shui Shi and Ruo-Xi Zhang and Jian-Feng Liu and Zeng-bo Ding and Lin Lu},
  journal={Journal of psychiatry & neuroscience : JPN},
  year={2013},
  volume={38 5},
  pages={306-16}
}
BACKGROUND Glutamate N-methyl-D-aspartate (NMDA) receptor antagonists exert fast-acting antidepressant effects, providing a promising way to develop a new classification of antidepressant that targets the glutamatergic system. In the present study, we examined the potential antidepressant action of 7-chlorokynurenic acid (7-CTKA), a glycine recognition site NMDA receptor antagonist, in a series of behavioural models of depression and determined the molecular mechanisms that underlie the… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

Beyond Ketamine: New Approaches to the Development of Safer Antidepressants

Current neuropharmacology • 2017
View 5 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 59 references

Acute D-serine treatment produces antidepressant-like effects in rodents.

The international journal of neuropsychopharmacology • 2012
View 1 Excerpt

Increased Cdk5/p35 activity in the dentate gyrus mediates depressive-like behaviour in rats.

The international journal of neuropsychopharmacology • 2012
View 1 Excerpt

Modulation of the extinction of two different fear-motivated tasks in three distinct brain

NG Fiorenza, J Rosa, I Izquierdo
areas. Behav Brain Res • 2012

Similar Papers

Loading similar papers…