Glycine release from radial cells modulates the spontaneous activity and its propagation during early spinal cord development.

@article{Scain2010GlycineRF,
  title={Glycine release from radial cells modulates the spontaneous activity and its propagation during early spinal cord development.},
  author={Anne-Laure Scain and Herv{\'e} Le Corronc and A F Allain and Emilie Muller and J. Rig{\'o} and Pierre Meyrand and Pascal Branchereau and Pascal Legendre},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2010},
  volume={30 1},
  pages={390-403}
}
Rhythmic electrical activity is a hallmark of the developing embryonic CNS and is required for proper development in addition to genetic programs. Neurotransmitter release contributes to the genesis of this activity. In the mouse spinal cord, this rhythmic activity occurs after embryonic day 11.5 (E11.5) as waves spreading along the entire cord. At E12.5, blocking glycine receptors alters the propagation of the rhythmic activity, but the cellular source of the glycine receptor agonist, the… CONTINUE READING
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