Glycine receptor alteration in the mutant mouse spastic


The mutant mouse spastic, which carries a single-locus, recessive mutation1 on chromosome 3 (refs 2, 3), is characterized by hyperexcitability, rapid tremor, rigidity and prolonged righting reflexes1. No anatomical abnormalities have been found in preliminary histological studies of muscle or the central nervous system (CNS)1. Electromyographic studies in… (More)
DOI: 10.1038/298655a0


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