Glycine-gated chloride current in acutely isolated rat hypothalamic neurons.

@article{Akaike1989GlycinegatedCC,
  title={Glycine-gated chloride current in acutely isolated rat hypothalamic neurons.},
  author={Norio Akaike and Makoto Kaneda},
  journal={Journal of neurophysiology},
  year={1989},
  volume={62 6},
  pages={
          1400-9
        }
}
1. Electrical and pharmacologic properties of glycine-induced currents were investigated in single hypothalamic neurons acutely isolated from young and adult rats by the use of a "concentration-clamp" technique, which allows both internal perfusion and rapid application of an external solution under single-electrode voltage-clamp. 2. The glycine-induced current reversed at the Cl- equilibrium potential (ECl), and a 10-fold decrease of extracellular Cl- with a large impermeable anion resulted in… CONTINUE READING

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