Glycine exerts dual roles in ischemic injury through distinct mechanisms.

  title={Glycine exerts dual roles in ischemic injury through distinct mechanisms.},
  author={Wenbing Yao and Fang Ji and Zheng Chen and Nan Zhang and Si-Qiang Ren and X. Zhang and Su-yi Liu and Wei Lu},
  volume={43 8},
BACKGROUND AND PURPOSE We characterized the differential effects of glycine at different levels in the induction of postischemic long-term potentiation, as well as in the neuronal damage induced by focal ischemia. METHODS Whole-cell patch clamp recordings were obtained from rat hippocampal slice preparations. In vitro ischemia and postischemic long-term potentiation were induced by oxygen and glucose deprivation. In vivo ischemia was induced by transient middle cerebral artery occlusion… CONTINUE READING
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