Glycine enhances expression of adiponectin and IL-10 in 3T3-L1 adipocytes without affecting adipogenesis and lipolysis

@article{Chen2018GlycineEE,
  title={Glycine enhances expression of adiponectin and IL-10 in 3T3-L1 adipocytes without affecting adipogenesis and lipolysis},
  author={Jingqing Chen and Xiaoshi Ma and Ying Guang Yang and Zhaolai Dai and Zhenlong Wu and Guoyao Wu},
  journal={Amino Acids},
  year={2018},
  volume={50},
  pages={629-640}
}
Glycine supplementation has been reported to enhance white-fat loss and improve sensitivity to insulin in animals with obesity or type 2 diabetes. However, the underlying mechanisms responsible for the beneficial effects of glycine remain largely unknown. The purpose of this study was to test the hypothesis that glycine regulates adipocyte differentiation, adipogenesis, and lipolysis, therefore, contributing to white-fat reduction. 3T3-L1 pre-adipocytes were induced to differentiate into… CONTINUE READING

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