Glycine-activated currents are changed by coincident membrane depolarization in developing rat auditory brainstem neurones.

@article{Backus1998GlycineactivatedCA,
  title={Glycine-activated currents are changed by coincident membrane depolarization in developing rat auditory brainstem neurones.},
  author={Kurt Harald Backus and Joachim W. Deitmer and Eckhard Friauf},
  journal={The Journal of physiology},
  year={1998},
  volume={507 ( Pt 3)},
  pages={783-94}
}
1. During early ontogeny, glycine receptors (GlyRs) exert depolarizing responses which may be of developmental relevance. We have used the gramicidin-perforated patch technique to elucidate the mechanism of glycine-activated currents in developing neurones of the rat lateral superior olive (LSO). 2. When the holding potential was set to -60 mV, perforated-patch recordings revealed glycine-induced inward currents in 59 %, outward currents in 5 % and biphasic currents in 34 % of the LSO neurones… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Afferent regulation of inhibitory synaptic transmission in the developing auditory midbrain.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2000
View 4 Excerpts
Highly Influenced

Role of bicarbonate and chloride in GABA- and glycine-induced depolarization and [Ca2+]i rise in fetal rat motoneurons in situ.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2000
View 4 Excerpts
Highly Influenced

[Regulation of intracellular chloride by cotransporters in developing lateral superior olive neurons].

Fukuoka igaku zasshi = Hukuoka acta medica • 2000
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…