Glycine Receptor Activation: When Three Out of Five Is Enough

Abstract

The prototypic member of the acetylcholine receptor family, the muscle nicotinic receptor, is a heteromeric complex with five subunits but only two ligand-binding sites. However, some members of this receptor superfamily are homomeric, containing five seemingly identical binding sites. Whether activation actually requires binding of five agonist molecules… (More)

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@inproceedings{Beato2004GlycineRA, title={Glycine Receptor Activation: When Three Out of Five Is Enough}, author={Marco Beato and Paul J. Groot-Kormelink and David Colquhoun and Lucia G Sivilotti and Rishard Salie and Markus Sigrist and Silvia Arber and T. Borsoi Klein and Walter Magerl}, year={2004} }