Glycine N-methyltransferase and regulation of S-adenosylmethionine levels.

@article{Luka2009GlycineNA,
  title={Glycine N-methyltransferase and regulation of S-adenosylmethionine levels.},
  author={Zigmund Luka and S. Harvey Mudd and Conrad Wagner},
  journal={The Journal of biological chemistry},
  year={2009},
  volume={284 34},
  pages={22507-11}
}
Methylation is a major biological process. It has been shown to be important in formation of compounds such as phosphatidylcholine, creatine, and many others and also participates in epigenetic effects through methylation of histones and DNA. The donor of methyl groups for almost all cellular methylation reactions is S-adenosylmethionine. It seems that the level of S-adenosylmethionine must be regulated in response to developmental stages and metabolic changes, and the enzyme glycine N… CONTINUE READING

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BIOLOGICAL CHEMISTRY 22511 by gest on July 31

  • Z. Luka
  • Vitam. Horm
  • 2008

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