Glycerophosphoinositols inhibit the ability of tumour cells to invade the extracellular matrix.

@article{Buccione2005GlycerophosphoinositolsIT,
  title={Glycerophosphoinositols inhibit the ability of tumour cells to invade the extracellular matrix.},
  author={Roberto Buccione and Massimiliano Baldassarre and Valentina Trapani and Carmen Catalano and A. C. L. Pompeo and Anna Brancaccio and Raffaella Giavazzi and Alberto Luini and Daniela Corda},
  journal={European journal of cancer},
  year={2005},
  volume={41 3},
  pages={470-6}
}
The naturally occurring phosphoinositide metabolite, glycerophosphoinositol 4-phosphate, has recently been shown to induce rearrangements in the actin cytoskeleton through modulation of the small GTPases, Rac and Rho. Since this is directly linked to cell spreading and remodelling, we have evaluated the potential role of glycerophosphoinositol 4-phosphate… CONTINUE READING