Glycerol neurolysis: neurophysiological effects of topical glycerol application on rat saphenous nerve.

@article{Burchiel1985GlycerolNN,
  title={Glycerol neurolysis: neurophysiological effects of topical glycerol application on rat saphenous nerve.},
  author={Kim Burchiel and Leslie Russell},
  journal={Journal of neurosurgery},
  year={1985},
  volume={63 5},
  pages={784-8}
}
The effect of topical glycerol application on normal and previously injured saphenous nerves was tested in 20 Sprague-Dawley rats. Anhydrous glycerol treatment of five normal nerves showed a rapid loss of C-fiber conduction within 5 minutes of application, while after 10 to 30 minutes, a complete conduction blockade in all fiber types was produced. The effect of anhydrous glycerol on both spontaneous firing from the neuroma and impulse propagation within the nerve was examined in 11 rats that… CONTINUE READING