Glycerol kinase-like proteins cooperate with Pld6 in regulating sperm mitochondrial sheath formation and male fertility

@inproceedings{Chen2017GlycerolKP,
  title={Glycerol kinase-like proteins cooperate with Pld6 in regulating sperm mitochondrial sheath formation and male fertility},
  author={Yuxi Chen and Puping Liang and Yan Huang and Minyan Li and Xiya Zhang and Chenhui Ding and Junyan Feng and Zhen Zhang and Xueqing Zhang and Yuanzhu Gao and Qinfeng Zhang and Shanbo Cao and Haiyan Zheng and Dan Liu and Zhou Songyang and Junjiu Huang},
  booktitle={Cell Discovery},
  year={2017}
}
Spermatids undergo the final steps of maturation during spermiogenesis, a process that necessitates extensive rearrangement of organelles such as the mitochondria. Male infertility has been linked to mitochondrial disorder, for example, hypospermatogenesis and asthenozoospermia. However, the mechanisms that regulate mitochondrial dynamics during spermiogenesis remain largely unknown. We found the glycerol kinase (Gyk)-like proteins glycerol kinase-like 1 (Gykl1) and glycerol kinase 2 (Gk2) were… CONTINUE READING
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