Glycerol dehydrogenase, encoded by gldB is essential for osmotolerance in Aspergillus nidulans.

@article{Vries2003GlycerolDE,
  title={Glycerol dehydrogenase, encoded by gldB is essential for osmotolerance in Aspergillus nidulans.},
  author={Ronald P de Vries and Simon J. Flitter and Peter J. I. van de Vondervoort and M K Chaveroche and Thierry Fontaine and Sabine Fillinger and George J. G. Ruijter and Christophe d'Enfert and J. Arjan G. M. de Visser},
  journal={Molecular microbiology},
  year={2003},
  volume={49 1},
  pages={131-41}
}
We have characterized the Aspergillus nidulans gldB gene encoding a NADP+-dependent glycerol dehydrogenase. A basal expression level was observed for gldB, which increased significantly under conditions of hyper-osmotic shock (1 M NaCl). Growth of strains in which gldB was disrupted was severely reduced on plates containing 1% glucose and 1 M NaCl, but these strains were able to grow on plates containing 1 M NaCl and 1% glycerol, arabitol, mannitol or erythritol. Uptake of these polyols… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

Similar Papers

Loading similar papers…