Glycemic variability: measurement and utility in clinical medicine and research--one viewpoint.

@article{Rodbard2011GlycemicVM,
  title={Glycemic variability: measurement and utility in clinical medicine and research--one viewpoint.},
  author={David Rodbard},
  journal={Diabetes technology & therapeutics},
  year={2011},
  volume={13 11},
  pages={1077-80}
}
One cannot control average glucose levels unless one first reduces glycemic variability! This sounds intuitively obvious and can also be demonstrated rigorously, mathematically. If the mean glucose level were 100 mg/dL but the SD were 40 mg/dL, one could predict that there would be an unacceptable incidence of severe hypoglycemia even though the mean glucose is in the euglycemic range. Clinicians must understand glycemic variability both qualitatively and quantitatively and endeavor to reduce… CONTINUE READING

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