Glycemic Variability: Assessing Glycemia Differently and the Implications for Dietary Management of Diabetes.

@article{Tay2015GlycemicVA,
  title={Glycemic Variability: Assessing Glycemia Differently and the Implications for Dietary Management of Diabetes.},
  author={Jeannie Tay and Campbell H. Thompson and Grant D. Brinkworth},
  journal={Annual review of nutrition},
  year={2015},
  volume={35},
  pages={
          389-424
        }
}
The primary therapeutic target for diabetes management is the achievement of good glycemic control, of which glycated hemoglobin (HbA1c) remains the standard clinical marker. However, glycemic variability (GV; the amplitude, frequency, and duration of glycemic fluctuations around mean blood glucose) is an emerging target for blood glucose control. A growing body of evidence supports GV as an independent risk factor for diabetes complications. Several techniques have been developed to assess and… 
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37 Citations
Background Citations
13
Methods Citations
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37 Citations

Citation Type

Citation Type

Association of glycemic variability and the anti-glycemic medication effect score in adults with type 2 diabetes
TLDR
From a range of patient characteristics, only the characteristic of a greater anti-glycemic medication score was significantly associated with greater GV in overweight or obese individuals with T2D, suggesting clinical targets for optimal glycemic management may require greater consideration of the impact of pharmacotherapy on GV.
Risk factors of pathological glycemic variability in pregnant women with type 1 diabetes mellitus
  • A. Tiselko
  • Medicine
    Journal of obstetrics and women's diseases
  • 2019
TLDR
CSII combined with CGM is the most optimal insulin therapy for glycemic targets achievement and glycemic variability reduction in T1D pregnant women without an increased risk for gly glucose variability and hypoglycemia.
Impact of Carbohydrate on Glucose Variability in Patients with Type 1 Diabetes Assessed Through Professional Continuous Glucose Monitoring: A Retrospective Study
TLDR
The performance of predictive models revealed the beneficial effect of adequate carbohydrate intake on glucose variation when combined with protein consumption, important for glucose stability and beneficial for patients with T1DM.
The Effect of Beta-Glucan Supplementation on Glycemic Control and Variability in Adolescents with Type 1 Diabetes Mellitus.
Association of various glycemic variability indices and vascular outcomes in type-2 diabetes patients
Abstract Both blood glucose (BG) level and glycemic variability (GV) significantly associate with diabetes-related complications. However, the criterion standard in GV assessment is absent. We aimed…
Assessment of blood glucose variability by continuous monitoring as a therapy guide for patients with diabetic nephropathy on hemodialysis
TLDR
CGM/MAGE have high specificity and sensitivity to measure variability of sugar levels, especially in patients with diabetic nephropathy on hemodialysis or not, in which HbA1c may not be a reliable tool.
Glycemic variability as a predictor of major adverse cardiac events after percutaneous coronary intervention
TLDR
It is proved that good controlling of acute shooting of blood glucose level up and down will improve the outcome in patient undergoing percutaneous coronary intervention (PCI) and greater GV is associated with composite MACE, especially for uncontrolled diabetic patients.
Efficacy of Real-Time Continuous Glucose Monitoring to Improve Effects of a Prescriptive Lifestyle Intervention in Type 2 Diabetes: A Pilot Study
TLDR
Preliminary evidence is provided that RT-CGM may be an effective strategy to optimise glucose control whilst following a low-carbohydrate lifestyle programme that targets improved glycaemic control, with minimal professional support.
Relative Contribution of Fasting and Postprandial Blood Glucose in Overall Glycemic Control: Post Hoc Analysis of a Phase IV Randomized Trial
TLDR
LM50 achieved better overall glycemic control than LM25 as a starter insulin in Chinese patients, which may be due to greater improvement in PPG levels.
Finding the clinical utility of 1,5-anhydroglucitol among primary care practitioners
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References

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