Glycated lysine-141 in haptoglobin improves the diagnostic accuracy for type 2 diabetes mellitus in combination with glycated hemoglobin HbA1c and fasting plasma glucose

@inproceedings{Spiller2017GlycatedLI,
  title={Glycated lysine-141 in haptoglobin improves the diagnostic accuracy for type 2 diabetes mellitus in combination with glycated hemoglobin HbA1c and fasting plasma glucose},
  author={Sandro Spiller and Yichao Li and Matthias Blueher and Lonnie R. Welch and Ralf Hoffmann},
  booktitle={Clinical Proteomics},
  year={2017}
}
  • Sandro Spiller, Yichao Li, +2 authors Ralf Hoffmann
  • Published in Clinical Proteomics 2017
  • Medicine
  • BackgroundRecent epidemiological studies indicate that only 30–50% of undiagnosed type 2 diabetes mellitus (T2DM) patients are identified using glycated hemoglobin (HbA1c) and elevated fasting plasma glucose (FPG) levels. Thus, novel biomarkers for early diagnosis and prognosis are urgently needed for providing early and personalized treatment.MethodsHere, we studied the glycation degrees of 27 glycation sites representing nine plasma proteins in 48 newly diagnosed male T2DM patients and 48 non… CONTINUE READING

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