Glycan profiling analysis using evanescent-field fluorescence-assisted lectin array: Importance of sugar recognition for cellular uptake of exosomes from mesenchymal stem cells.

@article{Shimoda2017GlycanPA,
  title={Glycan profiling analysis using evanescent-field fluorescence-assisted lectin array: Importance of sugar recognition for cellular uptake of exosomes from mesenchymal stem cells.},
  author={Asako Shimoda and Yoshiro Tahara and Shin-ichi Sawada and Yoshihiro Sasaki and Kazunari Akiyoshi},
  journal={Biochemical and biophysical research communications},
  year={2017},
  volume={491 3},
  pages={701-707}
}
Studies involving the functional analysis of exosomal contents including proteins, DNA, and RNA have been reported. Most membrane proteins and lipids are glycosylated, which controls their physical properties and functions, but little is known about glycans on exosomes owing to the difficulty of analysing them. To shed light on these issues, we collected exosomes from mesenchymal stem cells (MSCs) derived from human adipose tissue for glycan profiling using evanescent-field fluorescence… CONTINUE READING
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