Gluten Sensitivity in Pediatrics: A Clinical Conundrum

  title={Gluten Sensitivity in Pediatrics: A Clinical Conundrum},
  author={Fernanda Cristofori and Francesca Arezzo and Antonia Gentile and Ruggiero Francavilla},
  journal={Current Pediatrics Reports},
AbstractNon-celiac gluten sensitivity (NCGS) is a condition in which symptoms are triggered by gluten ingestion, in which both allergic and autoimmune mechanisms have been ruled out. The “classical” presentation of NCGS is a combination of gastrointestinal symptoms (including abdominal pain, bloating, and bowel habit abnormalities) and extra-intestinal manifestations. So far, NCGS has been described extensively in adults, and few data are available for the pediatric population. Due to lack of… 



Non-Celiac Gluten Sensitivity: The New Frontier of Gluten Related Disorders

The major advances and current trends on Non Celiac Gluten sensitivity are reported, including an overlap between the irritable bowel syndrome (IBS) and NCGS has been detected, requiring even more stringent diagnostic criteria.

Non-Celiac Wheat Sensitivity Is Not a New Entity

It seems that non-celiac wheat or gluten sensitivity may not be an entity but a syndrome as there is some evidence that the pathogenesis of this non-CEliac gluten sensitivity is diverse in different patients.

Non-celiac gluten sensitivity.

Gliadin does not induce mucosal inflammation or basophil activation in patients with nonceliac gluten sensitivity.

  • C. BucciF. Zingone C. Ciacci
  • Medicine
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • 2013

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Manifestations of food protein induced gastrointestinal allergies presenting to a single tertiary paediatric gastroenterology unit

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Gluten-sensitive diarrhea without evidence of celiac disease.