Gluten Causes Gastrointestinal Symptoms in Subjects Without Celiac Disease: A Double-Blind Randomized Placebo-Controlled Trial

@article{Biesiekierski2011GlutenCG,
  title={Gluten Causes Gastrointestinal Symptoms in Subjects Without Celiac Disease: A Double-Blind Randomized Placebo-Controlled Trial},
  author={J. Biesiekierski and E. Newnham and P. Irving and J. Barrett and M. Haines and J. Doecke and S. Shepherd and J. Muir and P. Gibson},
  journal={The American Journal of Gastroenterology},
  year={2011},
  volume={106},
  pages={508-514}
}
  • J. Biesiekierski, E. Newnham, +6 authors P. Gibson
  • Published 2011
  • Medicine
  • The American Journal of Gastroenterology
  • OBJECTIVES:Despite increased prescription of a gluten-free diet for gastrointestinal symptoms in individuals who do not have celiac disease, there is minimal evidence that suggests that gluten is a trigger. The aims of this study were to determine whether gluten ingestion can induce symptoms in non-celiac individuals and to examine the mechanism.METHODS:A double-blind, randomized, placebo-controlled rechallenge trial was undertaken in patients with irritable bowel syndrome in whom celiac… CONTINUE READING

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