Glutathione transferase activity and formation of macromolecular adducts in two cases of acute methyl bromide poisoning.

  title={Glutathione transferase activity and formation of macromolecular adducts in two cases of acute methyl bromide poisoning.},
  author={Robert Garnier and M O Rambourg-Schepens and Andre Mueller and Ernst Hallier},
  journal={Occupational and environmental medicine},
  volume={53 3},
OBJECTIVES To determine the activity of glutathione transferase and to measure the S-methylcysteine adducts in blood proteins, after acute inhalation exposure to methyl bromide. To examine the influence of the polymorphism of glutathione-S-transferase theta (GSTT1) on the neurotoxicity of methyl bromide. METHODS Two workers acutely exposed to methyl bromide with inadequate respiratory protective devices were poisoned. Seven weeks after the accident, blood samples were drawn from both patients… CONTINUE READING


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