Glutathione reverses the inhibition of T cell responses by superoptimal numbers of "nonprofessional" antigen presenting cells.

Abstract

"Professional" antigen-presenting cells (APC) such as macrophages or dendritic cells display not only antigens to specific T cell receptors but deliver in addition certain "costimulatory signals." Macrophages also release substantial amounts of cysteine and raise thereby the intracellular glutathione (GSH) levels of activated T cells in their vicinity. We… (More)

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@article{Roth1994GlutathioneRT, title={Glutathione reverses the inhibition of T cell responses by superoptimal numbers of "nonprofessional" antigen presenting cells.}, author={Stephan V Roth and Wulf Dr{\"o}ge}, journal={Cellular immunology}, year={1994}, volume={155 1}, pages={183-94} }