Glutathione redox imbalance in brain disorders

@article{Gu2015GlutathioneRI,
  title={Glutathione redox imbalance in brain disorders},
  author={Feng Gu and Ved Chauhan and Abha Chauhan},
  journal={Current Opinion in Clinical Nutrition and Metabolic Care},
  year={2015},
  volume={18},
  pages={89–95}
}
Purpose of reviewGlutathione (GSH) is a major endogenous antioxidant. Several studies have implicated GSH redox imbalance in brain disorders. Here, we summarize current evidence on how GSH depletion and GSH-related enzyme deficit are involved in the pathology of brain disorders such as autism, schizophrenia, bipolar disorder, Alzheimer's disease, and Parkinson's disease. Recent findingsMany studies with animal models of various brain disorders and/or with clinical samples from humans with… Expand
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