Glutathione prevents preterm parturition and fetal death by targeting macrophage-induced reactive oxygen species production in the myometrium.

@article{Hadi2015GlutathionePP,
  title={Glutathione prevents preterm parturition and fetal death by targeting macrophage-induced reactive oxygen species production in the myometrium.},
  author={Tarik Hadi and Marc Bardou and Guillaume Mac{\'e} and Pierre Sicard and Maeva Wendremaire and Marina Barrichon and Sarah Richaud and Oleg N. Demidov and Paul Sagot and Carmen Garrido and Fr{\'e}d{\'e}ric Lirussi},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2015},
  volume={29 6},
  pages={2653-66}
}
Preterm birth is an inflammatory process resulting from the massive infiltration of innate immune cells and the production of proinflammatory cytokines in the myometrium. However, proinflammatory cytokines, which induce labor in vivo, fail to induce labor-associated features in human myometrial cells (MCs). We thus aimed to investigate if reactive oxygen species (ROS) production could be the missing step between immune cell activation and MC response. Indeed, we found that ROS production is… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 2 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-6 of 6 extracted citations

Similar Papers

Loading similar papers…