Glutathione peroxidase3 of Saccharomyces cerevisiae protects phospholipids during cadmium-induced oxidative stress

@article{Muthukumar2011GlutathionePO,
  title={Glutathione peroxidase3 of Saccharomyces cerevisiae protects phospholipids during cadmium-induced oxidative stress},
  author={Kannan Muthukumar and Selvaraj Rajakumar and Mary Nirmala Sarkar and Vasanthi Nachiappan},
  journal={Antonie van Leeuwenhoek},
  year={2011},
  volume={99},
  pages={761-771}
}
The present study was undertaken to determine the role of glutathione peroxidase3 (gpx3) in phospholipid protection in cells. Wild-type (WT) cells showed an overall increase in phospholipids upon 50 μM cadmium (Cd)-treatment, whereas an untreated gpx3Δ strain showed a drastic reduction in overall phospholipids which was further reduced with 50 μM Cd. In WT cells, Cd-exposure increased the short chain fatty acids and decreased the unsaturated fatty acids and the magnitude was high in Cd-treated… 

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