Glutathione peroxidase enzyme activity in aging.

  title={Glutathione peroxidase enzyme activity in aging.},
  author={Sara E. Espinoza and Hongfei Guo and Neal S. Fedarko and Amy E Dezern and Linda P. Fried and Qian-Li Xue and Sean Leng and Brock A. Beamer and Jeremy D. Walston},
  journal={The journals of gerontology. Series A, Biological sciences and medical sciences},
  volume={63 5},
BACKGROUND It is hypothesized that free radical damage contributes to aging. Age-related decline in activity of the antioxidant enzyme glutathione peroxidase (GPx) may contribute to increased free radicals. We hypothesized that GPx activity decreases with age in a population of older women with disability. METHODS Whole blood GPx activity was measured in baseline stored samples from participants in the Women's Health and Aging Study I, a cohort of disabled community-dwelling older women… CONTINUE READING

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