Glutathione disulfide formation and lipid peroxidation during cardiac ischemia and reflow in the dog in vivo.

@article{Lenz1989GlutathioneDF,
  title={Glutathione disulfide formation and lipid peroxidation during cardiac ischemia and reflow in the dog in vivo.},
  author={M. L. Lenz and Lloyd H. Michael and Charles V Smith and Heather D Hughes and Scott B Shappell and A. A. Taylor and Mark L. Entman and Jerry R. Mitchell},
  journal={Biochemical and biophysical research communications},
  year={1989},
  volume={164 2},
  pages={722-7}
}
The content of glutathione disulfide (GSSG) in tissue, coronary sinus blood plasma, and in cardiac lymph was measured in a well-characterized model of regional cardiac ischemia and reflow in dogs in vivo in order to assess the magnitude of the oxidant stress produced. No increase in GSSG content was observed during 60 min of occlusion of the circumflex or… CONTINUE READING