Glutathione-associated enzymes in head and neck squamous cell carcinoma and response to cisplatin-based neoadjuvant chemotherapy.

Abstract

Glutathione S-transferases (GSTs) are metabolic phase II enzymes that promote reactive metabolite elimination by conjugating them to glutathione (GSH). Because of their important role in xenobiotic metabolism and detoxification, they have been implicated in carcinogenesis processes, especially epithelium transformation. Moreover, their influence on response… (More)

Topics

Cite this paper

@article{Cabelguenne2001GlutathioneassociatedEI, title={Glutathione-associated enzymes in head and neck squamous cell carcinoma and response to cisplatin-based neoadjuvant chemotherapy.}, author={Arnauld Cabelguenne and M A Loriot and Isabelle Stucker and H{\'e}l{\`e}ne Blons and Elisabeth Koum-Besson and Daniel F. Brasnu and P H Beaune and Ollivier Laccourreye and Pierre Laurent-Puig and Isabelle de Waziers}, journal={International journal of cancer}, year={2001}, volume={93 5}, pages={725-30} }