Glutathione S-transferase mu gene variants and colorectal cancer development--use of sequence-specific probes for an Iranian population.

@article{AghajanyNasab2011GlutathioneSM,
  title={Glutathione S-transferase mu gene variants and colorectal cancer development--use of sequence-specific probes for an Iranian population.},
  author={Monireh Aghajany-Nasab and Mojtaba Panjehpour and Siamak Mirab Samiee and Farzaneh Rahimi and Ahmad Movahedian},
  journal={Asian Pacific journal of cancer prevention : APJCP},
  year={2011},
  volume={12 6},
  pages={1511-5}
}
BACKGROUND Enzymes of the glutathione S-transferase (GST) family are encoded by a set of polymorphic genes as an important part of cellular chemical defense. The aim of this study was to investigate the possible effect of GSTM1 deletion on susceptibility to developing clinical outcome of colorectal cancer in a group of CRC patients from Isfahan province, Iran, in comparison to age and gender matched control group. METHODS DNA was extracted from blood of 140 CRC patients and 90 healthy… CONTINUE READING
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