Glutathione S-transferase T1 and M1: gene sequence variation and functional genomics.

Abstract

PURPOSE The glutathione S-transferases (GSTs) catalyze the glutathione conjugation of reactive electrophiles, including carcinogens and many antineoplastic drugs. GSTT1 and GSTM1 are polymorphically deleted, but the full range of genetic variation in these two genes has not yet been explored. We set out to systematically identify common polymorphisms in… (More)

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Cite this paper

@article{Moyer2007GlutathioneST, title={Glutathione S-transferase T1 and M1: gene sequence variation and functional genomics.}, author={Ann M Moyer and Oreste Ezequel Salavaggione and Scott J. Hebbring and Irene Moon and Michelle A. T. Hildebrandt and Bruce W. Eckloff and Daniel J. Schaid and Eric D. Wieben and Richard M. Weinshilboum}, journal={Clinical cancer research : an official journal of the American Association for Cancer Research}, year={2007}, volume={13 23}, pages={7207-16} }